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Gregor Hasler, MD

Professor of Psychiatry
Head, Department of Molecular Psychiatry
University Hospital of Psychiatry and Psychotherapy Bern

University of Bern
Bolligenstrasse 111
CH-3000 Bern 60

Phone: +41 31 930 99 74
Fax: +41 31 930 99 21
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Resilienz in der Psychiatrie und Politik

13. Berner Jahressymposium für Psychiater und Psychotherapeuten
Donnerstag, 21. Juni 2018 – 13:00 Uhr bis 17:00 Uhr – UPD Bern, Bolligenstrasse 111
Organisation und Leitung: Prof. Dr. Gregor Hasler, UPD Bern

Flyer und Programm




Behandlung von Depression mit Botulinumtoxin

Helfen Sie mit, neue Behandlungsmöglichkeiten gegen Depressionen zu erforschen!

Wir suchen Frauen und Männer im Alter zwischen 18 und 65 Jahren, die unter einer depressiven Störung leiden:

Und Frauen und Männer im Alter zwischen 18 und 65 Jahren, die in der nächsten Zeit entweder eine Faltenglättung mit Botulinumtoxin oder eine Faltenunterspritzung mit Hyaluronsäure an der Universitätsklinik für Dermatologie, Inselspital Bern, planen.


Die Depressionssprechstunde der Universitätsklinik für Psychiatrie und Psychotherapie Bern bietet unter der Leitung von Prof. Dr. med. Gregor Hasler eine ambulante Botulinumtoxin-Behandlung (Injektionen in die Stirn über der Nase) als neue Option der Behandlung von Depressionen an.

Diese neue Behandlungsoption richtet sich an Personen, die an leichten bis mittelgradigen depressiven Störungen leiden.

Wenn Sie Interesse an der Botulinumtoxin-Behandlung haben und weitere Informationen wünschen, können Sie uns gerne kontaktieren:

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med. pract. Irena Vladimirova, Assistenzärztin

Universitätsklinik für Psychiatrie und Psychotherapie
Bolligenstrasse 111, 3000 Bern 60
Telefon: 031 932 94 76
Fax: 031 932 82 83
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Gregor Hasler, M.D.

Professor of Psychiatry

Gregor Hasler, M.D. was born in Basel, Switzerland. He studied medicine at the University of Zurich and completed his psychiatric residency in Paris, London, Lausanne, and Zurich. He received his medical degree in 1995. He was trained in psychiatric epidemiology by Jules Angst, M.D., and published a series of longitudinal studies on the association between body weight and psychiatric conditions. From 2003 to 2006 he was a Visiting Research Fellow at the Mood and Anxiety Disorders Program at the National Institute of Mental Health (supervisors: Wayne C. Drevets, Dennis S. Charney, Dennis L. Murphy). Using PET imaging, magnetic resonance spectroscopy, pharmacological manipulations and genetics, he conducted a series of studies on biomarkers in mood, anxiety and eating disorders, and smoking (GABA, glutamate systems, catecholamines). In 2016, Dr. Hasler was visiting professor at the Icahn School of Medicine at Mount Sinai (Laboratory of Epigenetics, Dr. S. Akbarian). Since 2010, he is a Professor of Psychiatry at the University of Bern. His research is supported by the Swiss National Science Foundation, and he as has received numerous awards for his scientific work, including the NARSAD Independent Investigator Award and the Robert Bing Award from the Swiss Academy of Medical Sciences.

His major empirical findings include:

  • Identification of marked global reductions of metabotropic glutamate receptor 5 (mGluR5) in smokers and ex-smokers
  • Demonstration of abnormal mGluR5 binding in major depression
  • Experimental elucidation of the differential roles of serotonin and catecholamine deficiency in major depressive disorder
  • Discovery of a hypersensitivity to catecholamine depletion in bulimia nervosa
  • Discovery of dopamine-related learning dysfunction in bulimia nervosa
  • Elucidation of the relationship between dopamine neurotransmission, ghrelin and depression
  • Demonstration of reduced prefrontal GABA and glutamate concentrations in major depression
  • Elucidation of the relationship between dopamine neurotransmission, reward deficits and depression
  • Demonstration of a reduction in prefrontal GABA concentration as response to acute stress
  • Description of the serotonin-1a receptor pathology in comorbid temporal lobe epilepsy and depression
  • Discovery of the longitudinal association between short sleep duration and obesity
  • Contribution to the genetic epidemiology of OCD symptom dimensions

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=hasler+g

Dr. Hasler also contributed theoretical papers to psychiatry research, mainly about the endophenotype concept, the potential of computational psychiatry and the translation of research findings into practice.

Selected perspective review papers:

  • Hasler G, Drevets WC, Manji H, Charney DS (2004) Discovering endophenotypes for major depression. Neuropsychopharmacology 29:1765-1781
  • Hasler G, Northoff G (2011) Discovering imaging endophenotypes for major depression. Molecular Psychiatry 16: 604-619
  • Hasler G (2012) Can the Neuroeconomics revolution revolutionize psychiatry? Neuroscience and Biobehavioral Reviews 36: 64-78
  • Hasler G (2010) Pathophysiology of depression: do we have any solid evidence of interest to clinicians? World Psychiatry 9:155-161
  • Hasler G (2016) Well-Being: An Important Concept for Psychotherapy and Psychiatric Neuroscience. Psychotherapy and Psychosomatics, 85:255-61